Scientist* Early-Stage Formulation Process Development

Hiring By - Biostaffic

 BioPharma

Germany

Job Highlights

Not Disclosed

Posted 4 months ago
Job details
Become a member of the BioNTech Family!
As a part of our team of more than 5.000 pioneers, you will play a key role in developing solutions for some of the most crucial scientific challenges of our age. Within less than a year, we were able to develop our COVID-19 mRNA vaccine following the highest scientific and ethical standards – writing medical history.
We aim to reduce the suffering of people with life-changing therapies by harnessing the potential of the immune system to develop novel therapies against cancer and infectious diseases. While doing so, we are guided by our three company values: united, innovative, passionate. Get in touch with us if you are looking to be a part of creating hope for a healthy future in many people's lives.
Scientist* Early-Stage Formulation Process Development
As the Scientist* Early-Stage Formulation Process Development you will be responsible for the process development of new formulations for various lipid based formulations projects.
Your main responsibilities are:
  • Design and development of manufacturing processes for lipid nanoparticles towards mRNA delivery
  • Generate fundamental understanding on the manufacturing process of mRNA loaded lipid nanoparticles
  • Characterization and assessment of colloidal and chemical stability assessment of nanoformulations as a function of ageing
  • Data processing, evaluation, documentation of experiments, and writing of reports
  • Responsibility for instruments, laboratory management, and supervision of Student Assistants and Research Associate
  • Initiatives to improve the working efficiency within the team for example attending trainings and workshops for acquiring knowledge on the new technologies, automation of experimentations, data analysis, establishment of the orthogonal assays for rationalized development
What you have to offer:
  • Doctoral degree in pharmaceutical or other natural sciences (e.g., chemistry, biology, etc.)
  • Sound knowledge on the approaches to identify the critical quality attributes and critical process parameters for manufacturing of mRNA loaded lipid nanoparticles, industrial experience is a plus
  • Profound knowledge on chemical and biophysical characterization of lipid and polymer-based nanoparticle preparations ( e.g. , gel electrophoresis, SEC, DLS, zeta potential, fluorescence spectroscopy)
  • Insights on extended characterization techniques such as CD, SAXS, AF4, Cryo-TEM is a plus
  • Sound knowledge on the addition of functional excipients and other components to pharmaceuticals for enhancing the stability
  • Mechanistic understanding on the chemical and material properties and its implications on the subsequent processing will be beneficial
  • Experience with statistical analysis and data reporting software. (e.g., R-package, GraphPad, etc.)
  • An independent, responsible, and structured way of working as well as enthusiasm to participate in collaborative work projects
  • Fluent in English, verbal and written form
Benefits for you:
  • Flexible Working Time
  • Mobile Office
  • Work from EU Countries
  • Company Pension Scheme
  • Childcare
  • Jobticket
  • Company Bike
  • Leave Account
  • Fitness Courses
  • and much more.
Have we kindled your pioneering spirit?
Then apply now for our location Mainz iHub and simply send us your application documents using our online form.
If you have any further questions, our Talent Acquisition Team will be happy to answer them on + 49 (0) 6131-9084-1291 (monday-friday, from 12 noon to 4 pm).
Job-ID 6623 (please indicate for inquiries)
We look forward to your application!
  • BioNTech does not tolerate discrimination, favoritism, or harassment based on gender, political opinion, religion or belief, nationality, ethnic or social origin, age, sexual orientation, marital status, disability, physical appearance, health status or any other aspect of personal status. We are committed to creating a diverse and inclusive environment and are proud to be an equal opportunity employer. Most important – it’s a match!
BioNTech - As unique as you
www.biontech.com

Benefits Offered?

  • No

Bonus Offered?

  • No

Travel Required?

  • No

Location:

  • Germany

Global Experience Needed?

  • No

Specialized Experience Needed?

  • No

Apply before:

  • Apr 14, 2024
Company Overview
BioNTech SE
BioNTech SE

Current Openings: 0

At BioNTech we understand that every cancer patient’s tumor is unique and therefore each patient’s treatment should be individualized. To pioneer the next generation of patient-specific immunotherapies, we have combined ground-breaking research with cutting-edge technologies to develop therapeutics for cancer and beyond. Our broad and synergistic suite of platforms, which include mRNA therapeutics, engineered cell therapies, antibodies and small molecule immunomodulators have been optimized for distinct modes of action, high precision targeting, high potency and efficacy. We are also developing in parallel our own state-of-the-art manufacturing processes to complement our drug development platforms. We were founded in 2008 in Mainz, Germany and have been driven to become the leading global biotechnology company for individualized cancer medicine. We have over 20 product candidates in development, 8 candidates in 9 ongoing clinical trials, treated over 250 patients across 17 tumor types and supported by more than 1100 employees. As we prove the value of our approach in the clinic, we continue to build a network of world-class corporate and scientific collaborators, manufacturing and team required to bring individualized treatments to patients worldwide. To learn more about us, visit https://biontech.de/ Our privacy statement can be found here: https://www.biontech.com/int/en/home/data-privacy-statement.html
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