Senior Scientist, LBA LCMS

The Role:
Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology with a diverse pipeline of development programs across various diseases. As an employee, you'll be part of a continually growing organization working alongside exceptional colleagues and strategic partners worldwide, contributing to global health initiatives. Moderna's commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience with the potential to make a significant impact on patients' lives worldwide.
Moderna's strategic partnership with the UK Government is exemplified by our innovative presence at Harwell. Our mission is to establish a leading-edge research, development, and manufacturing facility as part of a long-term commitment to onshore mRNA vaccine production for respiratory diseases. This initiative will create a multitude of highly skilled jobs and foster collaboration with academic and NHS partners across the UK. We're looking for global experts eager to join us in this endeavor, contributing to a future where access to life-saving vaccines is a reality for all .
Moderna is seeking an experienced Bioanalytical Senior Scientist to join the Bioanalytical and Molecular Assays team to support regulated clinical trials. A successful incumbent would help integrate basic science research, bioanalysis, and informatics to move programs into the clinic as well as reverse-engineer clinical findings to novel opportunities for Moderna’s pipeline.
Here’s What You’ll Do:
Your key responsibilities will be:

• Design and execution of phase-appropriate bioanalytical strategies including immunogenicity, quantitation of therapeutic proteins, lipid characterization, and PK/PD assay method development and validation.
• Ensuring assays are developed in a timely manner to meet program timelines, the qualification or validation of assays is fit for purpose, and troubleshoot any issues that arise internally or with external CRO partners.
• Development of PK/PD and ADA/Tab/NAb assays using ELISA, MSD, cell culture, and other relevant technologies.
• Establishing internal and external ASO bioanalytical capability and facilitating method development to support Moderna’s portfolio.
• Supervising junior Scientist and Research associates, and collaborating with preclinical and clinical operations and sample management to define sample journey and develop appropriate laboratory manuals.
  

Your responsibilities will also include:

• Analytical equipment procurement/qualifications, preparation and maintenance of SOP’s, determination, and control of critical reagents.
  

The key Moderna Mindsets you’ll need to succeed in the role:

• Pursue options in parallel: Effectively managing multiple tasks and projects to ensure the best outcomes through a comprehensive approach.
• Dynamic range: Demonstrating the capacity to drive both strategy and execution, adapting swiftly to new data and changing priorities.
  

Here’s What You will Bring to the Table:

• A Ph.D. in infectious disease, Immuno-oncology, Immunology, Cancer Biology, or related fields and a minimum of 7 years of industry biotech/pharmaceutical experience. M.S. with extensive bioanalytical experience (i.e. 10 years) are also considered
• Experience with RNA, Antibodies, biologics and cell therapy preferred
• Expert knowledge of various ligand bind binding assay platforms such as ECL, Gyrolabs, immunoassays, bDNA and other methodologies for pre-clinical and clinical assays is preferred Experience with genetic assays such as qPCR and ddPCR is a plus
• Experience with cell culture would be an advantage
• Working knowledge of the translational literature and competitive landscape in the mRNA field.
• Ability to effectively communicate scientific concepts, program objectives, data analysis within a matrix environment.
• Deep knowledge of GLP and GCP requirements and understanding of current industry trends and regulatory expectations associated with bioanalytical science.
  

Moderna offers personalized benefit programs and well-being resources as unique as our global workforce so employees can do their best work.
We recognize and appreciate your diverse needs and interests and do our best to support you at work and at home with:

• Quality healthcare and insurance benefits
• Lifestyle Spending Accounts to create your own pathway to well-being
• Free premium access to fitness, nutrition, and mindfulness classes
• Family planning and adoption benefits
• Generous paid time off, including vacation, bank holidays, volunteer days, sabbatical, and a discretionary year-end shutdown
• Educational resources
• Savings and investments
• Location-specific perks and extras!
  

The benefits offered may vary depending on the nature of your employment with Moderna and the country where you work.
About Moderna
Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.
By living our mission, values, and mindsets every day, our people are the driving force behind our scientific progress and our culture. Together, we are creating a culture of belonging and building an organization that cares deeply for our patients, our employees, the environment, and our communities.
We are proud to have been recognized as a Science Magazine Top Biopharma Employer, a Fast Company Best Workplace for Innovators, and a Great Place to Work in the U.S.
If you want to make a difference and join a team that is changing the future of medicine, we invite you to visit modernatx.com/careers to learn more about our current opportunities.
Moderna is a smoke-free, alcohol-free and drug-free work environment.
Moderna is a place where everyone can grow. If you meet the Basic Qualifications for the role and you would be excited to contribute to our mission every day, please apply!
Moderna is proud to be an equal opportunity workplace and is an affirmative action employer.
Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry or citizenship, ethnicity, disability, military or protected veteran status, genetic information, sexual orientation, marital or familial status, or any other personal characteristic protected under applicable law. Moderna is an E-Verify Employer in the United States. We also consider qualified applicants regardless of criminal histories, consistent with legal requirements.
Belonging, Inclusion, and Diversity are critical to the success of our company and our impact on society. We’re focused on attracting, retaining, developing, and advancing our employees and believe that by cultivating diverse experiences, backgrounds, and ideas, we can provide an environment where every employee is able to contribute their best.
Moderna is committed to offering reasonable accommodations to qualified job applicants with disabilities. Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the Talent Acquisition Partner or contact the Accommodations team at leavesandaccommodations@modernatx.com. (EEO/AAP Employer)
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